Personally, I think this question may have been closed a bit too quickly. It's true that subjective questions don't work as well in the Stack Exchange format as objective ones. However, that doesn't mean that no subjective questions are welcome here. There are good and bad subjective questions. The bad ones tend to be a large majority on our site, but the good ones are arguably some of the most valuable questions, and shouldn't be closed.
The close reason used was "primarily opinion based", which is not synonymous with "subjective"; a question is primarily opinion based when all answers are equally valid and there's no method to distinguish between good and bad. I think everyone here can agree that, for example, Nausicaä and Neon Genesis Evangelion are more important in the history of anime than Buso Renkin or So Ra No Wo To, regardless of which of these you actually enjoyed more. There's nothing really opinionated about that.
With that said, I'm not yet going to nominate the question for reopening. As of right now, the question is rather broad. You haven't narrowed down exactly what you want. Designing a full course, complete with lectures, is obviously too broad for this site. Are you looking for just a syllabus of what sort of topics might be covered and approximately how much time will be spent on each? That could potentially work. There's a bit of opinion in which topics are more and less important, but honestly there's barely even enough time in one semester to cover the stuff that we'd all agree is important.
What would the goal of this class be? To educate people about the general trends in anime/manga history? Or to get people to the point at which they can catch most of the obvious references in the average comedy series that airs these days? Or to understand Japanese culture better by studying the particular case of anime in depth? Also, how much anime do you expect the average student will have seen going in? Each of these would require a very different syllabus.
What format of class are you planning? Are you going to show anime during lecture? Or are you going to lecture and let people watch on their own time as "homework"? Or some combination? This is important because it determines how much time you have available to you. If you're going to be showing most of it during lecture, that limits the amount that you can cover in depth pretty severely.
There's a host of similar issues that could also use clarification. It seems like you want us to answer these, but that's where your question is getting too broad and subjective. Generally, the more you can tell us about what you want, the better your question is. If you can tell us the format and goal of the class, I think we'd be able to tell you what the major time periods and themes were. If you can address some of those points above to focus your question better, I'd consider voting to reopen it.
Alternatively, I think the sub-question of whether there are any existing college courses on anime history is already basically fine for this site. I don't think there's more than a handful of such classes.
To make an analogy, if you asked "What should be taught in an introductory college English course?" on English SE, you'd probably get a similar response. The question is too free-form to work on a Stack Exchange site. There are simply too many options, and designing a course from scratch is too big an undertaking for a single question. But if you focused your question more, e.g. "What works of Hemingway would best show the evolution of his literary style in the context of a college freshman writing seminar?" and provided details in the question as to what broad topics you want to cover in the course, it would be a much better question (though off-topic on English SE which doesn't cover literature).